If I'm using pucks, I run 24/7.

Once I start on bleach, I run about 12 hrs/day.

Of course run time is going to be dependent on many issues such as proximity to trees, hours of direct sunlight, bather load, etc, etc, etc. Those issues will determine the need to run more than any other issue.

My pool is close to a number of trees, so leaves and bugs are plentiful. Running 24/7 cuts down on dirt on the bottom of the pool. It also helps me keep my water more evenly balanced.