The are two situations where a split run time can help. First, if you get a lot of debris falling into the pool over a 24 hr period, then running the skimmers twice a day would reduce the amount of debris getting to the pool floor. The other time it has value is when you live in an area where the UV extinction is really high (e.g. AZ). But that can usually be combated by a higher CYA so even there it may not be totally necessary unless there is an aversion to higher CYA.

But if you have the capability to do a split run time, it certainly doesn't hurt and for the first reason, can help.